Giovanni L Beretta Selected Research

IDN5174

11/2006

Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.

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Giovanni L Beretta Research Topics

Disease

18	Neoplasms (Cancer) 07/2023 - 07/2003
7	Carcinoma (Carcinomatosis) 03/2011 - 09/2002
4	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 04/2015
3	Melanoma (Melanoma, Malignant) 01/2023 - 01/2022
2	Neoplasm Metastasis (Metastasis) 01/2023 - 01/2023
2	Breast Neoplasms (Breast Cancer) 11/2015 - 07/2004
1	Mesothelioma 04/2024
1	Inflammation (Inflammations) 04/2024
1	Cardiotoxicity 07/2023
1	Hepatocellular Carcinoma (Hepatoma) 01/2023
1	Infections 01/2023
1	Stomach Neoplasms (Stomach Cancer) 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Starvation 01/2022
1	medullary Thyroid cancer 08/2016
1	Ovarian Epithelial Carcinoma 01/2013
1	Ovarian Neoplasms (Ovarian Cancer) 03/2011
1	Genomic Instability 08/2008
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2006
1	Urinary Bladder Neoplasms (Bladder Cancer) 02/2005

Drug/Important Bio-Agent (IBA)

4	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 09/2002
3	Antineoplastic Agents (Antineoplastics)IBA 07/2023 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2023 - 08/2008
3	PlatinumIBA 01/2013 - 09/2002
3	CamptothecinIBA 03/2010 - 02/2005
2	Peptides (Polypeptides)IBA 01/2023 - 07/2015
2	VemurafenibIBA 01/2023 - 01/2022
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2017 - 07/2004
2	Small Interfering RNA (siRNA)IBA 03/2016 - 07/2015
2	RetinoidsIBA 03/2011 - 07/2005
2	3- (4'- hydroxy- 3'- adamantylbiphenyl- 4- yl)acrylic acidIBA 03/2011 - 07/2005
2	Topotecan (Hycamtin)FDA LinkGeneric 11/2006 - 02/2005
2	ST 1481 (Gimatecan)IBA 02/2005 - 07/2004
1	AsbestosIBA 04/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023
1	Amino Acids FDA Link 01/2023
1	Kisspeptin-1 ReceptorsIBA 01/2023
1	KisspeptinsIBA 01/2023
1	IronIBA 01/2023
1	avasimibeIBA 01/2022
1	Proto-Oncogene Proteins B-rafIBA 01/2022
1	CholesterolIBA 01/2022
1	EnzymesIBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2022
1	LipidsIBA 01/2022
1	PhytochemicalsIBA 01/2021
1	ResveratrolIBA 01/2021
1	Androgen Receptors (Androgen Receptor)IBA 01/2019
1	AnthraquinonesIBA 12/2017
1	AnthracyclinesIBA 12/2017
1	Topoisomerase I InhibitorsIBA 01/2017
1	naphthalenediimideIBA 08/2016
1	Messenger RNA (mRNA)IBA 03/2016
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 03/2016
1	ErbB Receptors (EGF Receptor)IBA 03/2016
1	fragile histidine triad proteinIBA 11/2015
1	Epidermal Growth Factor (EGF)IBA 11/2015
1	Proteasome InhibitorsIBA 11/2015
1	DisulfidesIBA 07/2015
1	SurvivinIBA 07/2015
1	Nucleic AcidsIBA 07/2015
1	PolymersIBA 04/2015
1	multidrug resistance-associated protein 1IBA 01/2013
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2013
1	3- (3'- adamantan- 1- yl- 4'- methoxybiphenyl- 4- yl)- 2- propenoic acidIBA 03/2011
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 03/2010
1	Adenosine Triphosphate (ATP)IBA 03/2010
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2006
1	IDN5174IBA 11/2006
1	DNA (Deoxyribonucleic Acid)IBA 07/2005
1	LactonesIBA 07/2004
1	BBR 3464 (BBR3464)IBA 07/2003

Therapy/Procedure

5	Therapeutics 07/2023 - 01/2016
2	Drug Therapy (Chemotherapy) 01/2016 - 01/2013
1	Radiotherapy 01/2023